Our Science

Knowledge is power - understand your unique biology and empower yourself to live a better, healthier & younger life!

Using the power of biology to engineer your younger future

We are applying the latest scientific discoveries in genetics, cellular biology and nutrition science combined with advanced machine learning to understand the complex and intertwining biological mechanisms of ageing. This gives us a unique ability to target these mechanisms systemically and is the foundation of our unique platform and personalised supplementation, which stems from the molecular basis of the Hallmarks of Aging.

Our cells and organs are “designed” to regenerate and repair with much of our genome and immune system dedicated to these functions.

These repair processes weaken and stop working as we age leading to frailty, degeneration and systemic decline of function.

The decline is reversible and repair processes can be restarted and cells rejuvenated.

Our cells and organs are “designed” to regenerate and repair with much of our genome and immune system dedicated to these functions.

These repair processes weaken and stop working as we age leading to frailty, degeneration and systemic decline of function.

The decline is reversible and repair processes can be restarted and cells rejuvenated.

Biological age and why does it matter?

Chronological age measures how many birthdays you celebrated, but it has only a little relevance on how you feel.

Biological age reflects how well your physiological and mental processes are working and more importantly, it can be influenced by lifestyle choices.

With the right longevity interventions and lifestyle choices, biological age can be reversed and uncoupled from chronological age.

Get to know your Biology

Our unique AI-driven longevity insights are built on the foundation of your genetics with the added value of your blood physiology and microbiome profile completing the holistic view of your functional biology. They form the basis for our personalised approach to our products and services – to provide you with the most up to date and science-backed supplementation and longevity recommendations.

The Hallmarks of Aging

At Longevize we have developed a unique formula of nutritional supplements, which actively act upon all key Hallmarks of aging.

STEM CELL EXHAUSTION
CELLULAR SENESCENCE
EPIGENETIC ALTERATIONS
DECLINE IN MICROBIOME DIVERSITY
MITOCHONDRIAL DYSFUNCTION
DEREGULATED NUTRIENT SENSING
LOSS OF PROTEOSTASIS
TELOMERE ATTRITION
GENOMIC INSTABILITY
ALTERED INTERCELULAR COMMUNICATION
STEM CELL EXHAUSTION

Activities of stem cells, which help in regenerating new tissue cells, decline with aging.

CELLULAR SENESCENCE

Sometimes an aging cell, instead of recycling, turns into a dormant "senescent" cell, which not only stops performing its biological function, but can influence neighbouring cells to become senescent as well. Accumulation of such "Zombie Cells" leads to loss of tissue function, inflammation and many harmful health effects that drive the aging process.

EPIGENETIC ALTERATIONS

Like bookmarks in our genome cookbook, epigenetic marks are all over our genes informing when they should be transcribed in response to individual’s life experiences or environmental factors.

DECLINE IN MICROBIOME DIVERSITY

The microbial diversity of our gut declines with age and becomes less helpful in terms of metabolic processes. This leads to a reduced ability to digest food, uptake important nutrients as well as contributing to inflammation and other health problems of ageing.

MITOCHONDRIAL DYSFUNCTION

Mitochondria (the energy powerhouse of the cell) are exposed to a continuous onslaught of free radicals as they produce the energy necessary to sustain life. In younger cells, mitochondria are regularly recycled (mitophagy) and new mitochondria are made (biogenesis) but with age, these processes decline, and malfunctioning mitochondria start to accumulate, subsequently causing excessive free radical stress and depletion of available cellular energy.

DEREGULATED NUTRIENT SENSING

Proteins and pathways, which control cellular metabolism are influenced by sensing nutrient levels; in time, these sensory mechanisms get disrupted and dysregulated, leading to onset of many age-related diseases and aging.

LOSS OF PROTEOSTASIS

With age, cellular proteins become misfolded and lose their functions. A young cell can refold or recycle such proteins, but with age this ability of protein repair declines.

TELOMERE ATTRITION

Over time the protective "caps" at the end of chromosomes shorten, resulting in cells not being able to divide anymore, which can lead to disease, cellular senescence or cellular death.

GENOMIC INSTABILITY

Throughout one's life, both internal and external factors cause genetic damage. The ability to repair this damage declines with age and mutations start to build up and further accelerate aging.

ALTERED INTERCELULAR COMMUNICATION

Communication between cells is disrupted with age, resulting in inflammation and tissue damage.

Roadmap to Personalisation

Unique formula to systematically target Hallmarks of Aging

Providing maximal support for cellular processes involved in longevity, reversing the mechanisms of ageing and boosting your energy, vitality, metabolic strength and cognitive performance.

Unique formula to systematically target Hallmarks of Aging

Providing maximal support for cellular processes involved in longevity, reversing the mechanisms of ageing and boosting your energy, vitality, metabolic strength and cognitive performance.

Tailoring to your Genes and Blood tests

Our longevity supplement formula will be fine-tuned to your unique genetic profile making sure it provides the optimal support for your unique set of genes and taking into account all your biological strengths and weaknesses. This is then further adjusted based on your blood biomarkers for any specific needs or deficiencies, which may have resulted from your current diet and lifestyle.

Tailoring to your Genes and Blood tests

Our longevity supplement formula will be fine-tuned to your unique genetic profile making sure it provides the optimal support for your unique set of genes and taking into account all your biological strengths and weaknesses. This is then further adjusted based on your blood biomarkers for any specific needs or deficiencies, which may have resulted from your current diet and lifestyle.

The final microbial touch

Our body – our life’s vehicle is also a host to trillions of bacteria that help with digestion, support our immune defences and even impact our mood and cognitive function. The final modification of our formula takes into account each individual’s microbiome and how to support its health in the best way possible.

The final microbial touch

Our body – our life’s vehicle is also a host to trillions of bacteria that help with digestion, support our immune defences and even impact our mood and cognitive function. The final modification of our formula takes into account each individual’s microbiome and how to support its health in the best way possible.

Science is one of our core pillars, hence our approach is based on cutting-edge discoveries and constantly kept up to date with our team of scientists as well as world-leading KOLs.

Science is one of our core pillars, hence our approach is based on cutting-edge discoveries and constantly kept up to date with our team of scientists as well as world-leading KOLs.

Ready to understand your body?